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Résumé Un risque modérément accru de cancer, en particulier digestif, est bien établi chez les sujets diabétiques de type 2 ou ayant des anomalies mineures de glyco-régulation. Cette association semble passer par l’hyperinsulinémie liée à l’insulinorésistance et par l’influence de l’insuline et des facteurs de croissance sur la prolifération cellulaire. Le rôle de l’hyperglycémie dans cette relation...
A moderate increase in cancer risk has been shown in diabetic patients and in individuals with abnormal glucose tolerance, mainly for digestive sites, independently of obesity, with in contrast, a protective effect for prostate cancer. Insulin-resistance with compensatory hyperinsulinemia, and elevated levels of circulating growth factors are usually considered to be the link between cancer and hyperglycaemia,...
Objective: To report two cases of testicular cancer in patients presenting with infertility.Design: Case reports.Setting: University-affiliated urology practice.Patient(s): Two men presenting with infertility.Intervention(s): Complete history and physical, hormonal assays, semen analysis, scrotal ultrasound, radical orchiectomy.Main Outcome Measure(s): Testicular pathology specimens.Result(s): Testicular...
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