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Background and ObjectivesGranulocyte‐reactive antibodies can cause autoimmune and neonatal immune neutropenias as well as transfusion‐related acute lung injury. The classical antibody‐detection methods granulocyte aggregation test (GAT), granulocyte immunofluorescence test (GIFT) and monoclonal antibody‐specific immobilization of granulocyte antigens (MAIGA) are time‐consuming and technically challenging...
Granulocyte‐reactive antibodies may cause transfusion‐related acute lung injury (TRALI) and immune neutropenias. Risk factors for their acquisition other than previous alloexposition are largely unknown. In addition to the known association between human leucocyte antigen alloantibodies and red blood cell alloimmunization in selected cohorts of transfused patients, this study investigated a possible...
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