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Allo‐antibodies produced by K‐negative pregnant women against a fetal K antigen from the Kell blood group system may cause hemolytic disease of the fetus and newborn (HDFN). Predicting the fetal K antigen using noninvasive prenatal testing (NIPT) is important for decisions concerning management of pregnancies. Digital and droplet digital PCR techniques permit the detection of fetal single nucleotide...
BackgroundBlood donors exhibiting a weak D or DEL phenotypical expression may be mistyped D– by standard serology hence permitting incompatible transfusion to D– recipients. Molecular methods may overcome these technical limits. Our aim was to estimate the frequency of RHD alleles among the apparently D– Polish donor population and to characterize its molecular background.
Study Design and MethodsPlasma...
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