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BACKGROUNDThe presence of human leukocyte antigen donor‐specific antibodies (DSAs) increases the risk of graft failure in T‐cell–replete haploidentical hematopoietic stem cell transplantation (haplo‐HSCT)
CASE REPORTA 49‐year‐old female with high‐risk acute myeloid leukemia in first complete remission received a haplo‐HSCT from her daughter. Pretransplant recipient screening examination showed high...
The development of solid-phase assays for antibody detection has aided in the frequent detection of human leukocyte antigen (HLA) antibodies in nonalloimmunized males. Some scientists have reported that these HLA antibodies are produced to pathogens or allergens and the reactivity with HLA coated beads is the result of cross-reactive epitopes. These antibodies may also be directed toward cryptic epitopes...
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