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AimVarious components of metabolic syndrome associate with cardiac intracellular calcium () mishandling, a precipitating factor in the development of heart failure. We aimed to provide a thorough description of early stage ‐cycling alterations in the fructose‐fed rat, an experimental model of the disorder, where insulin resistance, hypertension and dyslipidaemia act cooperatively on the...
The effects of proteosome inhibitor Bortezomib (BZ) were studied in vitro for 24 h on the protein kinase C (PKC) profiles, rates of proliferation and apoptosis in Jurkat cells and lymphocytes of 10 patients with systemic lupus erythematosus (SLE) and nine healthy subjects. The expressions of PKC proteins, the rates of proliferation and apoptosis were determined. The effects of BZ were different in...
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