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Background
Management of preschool wheeze is based predominantly on symptom patterns.
Objective
To determine whether personalizing therapy using blood eosinophils or airway bacterial infection results in fewer attacks compared with standard care.
Methods
A proof‐of‐concept, randomized trial to investigate whether the prescription of inhaled corticosteroids (ICS) guided by blood eosinophils, or...
Little is known about adherence to inhaled corticosteroids (ICS) in preschool children with troublesome wheeze. Children with aeroallergen senitization, or those reporting multiple trigger wheeze (MTW), are more likely to respond to ICS. We hypothesized that adherence to ICS and symptom control are only positively related in atopic children, or those reporting MTW. Patients aged 1 to 5 years with...
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