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This review deals with individual components regulating the neural control of the urinary bladder. This article will focus on factors and processes involved in the two modes of operation of the bladder: storage and elimination. Topics included in this review include: (1) The urothelium and its roles in sensor and transducer functions including interactions with other cell types within the bladder...
The basic premise of this symposium (Workshop 7) at the 2004 International Continence Society meeting in Paris was to elucidate different mechanisms of urothelial cell pathology, explore their impact on bladder function and discuss novel therapeutic interventions. The topics included 1) urothelial structure and function, 2) the role of adenosine triphosphate in urothelial signaling and cystitis,...
Nerve conduction block induced by high frequency biphasic electrical current was simulated using a lumped circuit model of the myelinated axon based on Frankenhaueuser-Huxley (FH) equations. Axons of different diameters (5-20 mum) can be blocked completed when the stimulation frequency is above 10 kHz. At higher frequency a higher stimulation intensity is needed to block nerve conduction. Larger diameter...
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