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Improved diagnostic tests for tuberculosis (TB) among people with human immunodeficiency virus (HIV) are urgently required. We hypothesized that methylation‐driven genes (MDGs) of host blood could be used to diagnose patients co‐infected with HIV/TB. In this study, we identified three MDGs among patients with HIV monoinfection and those with HIV/TB co‐infection using the R package MethylMix. We then...
Tuberculosis (TB) is one of the most common opportunistic infections and a leading cause of death in patients infected with human immunodeficiency virus (HIV). However, conventional diagnostic tools have several limitations. The aim of this study was to screen key DNA methylated cytosine‐phosphate‐guanine dinucleotide (CpG) islands (CGIs) to identify potential diagnosis biomarkers in HIV mono‐infected...
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