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The mammalian target of rapamycin (mTOR)/p70S6 kinase (S6K) pathway plays an important role in brain‐derived neurotrophic factor (BDNF)‐mediated protein synthesis and neuroplasticity. Although many aspects of neuronal function are regulated by intracellular calcium ([Ca2+]i) and calmodulin (CaM), their functions in BDNF‐induced phosphorylation of p70S6K and protein synthesis are largely unknown. Here,...