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Background
Although glutathione (GSH) has long been considered a master antioxidant, poor stability and bioavailability limit its application in skin protection. To overcome the challenges, Unilever R&D formulated a Glutathione Amino acid Precursors blend (named GAP) to boost GSH de novo synthesis.
Objective
Determine whether GAP can boost GSH levels and provide skin protection against stressors...
Background
UV radiation exposure causes skin irritation, erythema, darkening and barrier disruption by inducing oxidative stress and inflammation. Glutathione, a master antioxidant, plays an important role in the antioxidant defence network of the skin.
Objective
This study aimed to assess the in vitro protective effects of the glutathione amino acid precursors blend (GAP) on transcriptomic and...
Background
Since air pollution is only one of many environmental stressors that can affect skin, it has been challenging to identify skin appearance or functional features profoundly affected by chronic exposure to traffic‐derived air pollution.
Aims
The current population study focused on taxi drivers working in urban and rural areas in order to take advantage of difference in occupational exposure...
Skin surface is constantly exposed to environmental and secreted stressors such as UV, air pollution and peroxidized sebum. The current study aims to use reconstructed human skin equivalents to demonstrate topical stressor‐induced hyperpigmentation and evaluate bioactives’ potential protective effect. Given that polycyclic aromatic hydrocarbons are representative airborne particle‐bound organic compounds...
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