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Transforming growth factor β1 (TGF‐β1), a multifunctional cytokine, is known to promote tumor invasion and metastasis and induce epithelial‐mesenchymal transition (EMT) in various cancer cells. Inhibition of TGF‐β1 signaling is a new strategy for cancer therapy. Most cancer cells display altered or nonfunctional TGF‐β1 signaling; hence, TGF‐β1 inhibitors exert limited effects on these cells. Recent...
We evaluated the content and biochemical properties of chondroitin sulfate (CS) in shark cartilage powders being used as nutraceutical supplements. The quantities of CS in shark cartilage products (SCPs) and finished products containing shark cartilage powder were determined by analyzing unsaturated disaccharides after treatment with chondroitinase ABC, and the results were compared with the specifications...
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