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Metabolic pathways have emerged as cornerstones in carcinogenic deregulation providing new therapeutic strategies for cancer management. Recently, a new branch of cholesterol metabolism has been discovered involving the biochemical transformation of 5,6‐epoxycholesterols (5,6‐ECs). The 5,6‐ECs are metabolized in breast cancers to the tumour promoter oncosterone whereas, in normal breast tissue, they...
Regulatory T (Treg) lymphocytes play a central role in the control of immune responses and so maintain immune tolerance and homeostasis. In mice, expression of the CD8 co‐receptor and low levels of the co‐stimulatory molecule CD28 characterizes a Treg cell population that exerts potent suppressive function in vitro and efficiently controls experimental immunopathology in vivo. It has remained unclear...
Mobile technology has become a staple in our society. It plays a crucial and profound role inassisting learners (despite their level and age) in their leaning process using various apparatus and mobile devices (laptop, tablets …). This paper presents a new learning framework based on tablets. This solution has been developed and tested in Esprit "Ecole Supérieure Privée d'Igénieurie et de Technologies",...
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