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ObjectivesFibroblast growth factor 23 (FGF23) has been associated with cardiovascular mortality. We estimate associations between the level of plasma FGF23 and exposure to abacavir (ABC) and to other components of antiretroviral therapy in patients co‐infected with HIV and hepatitis C.
MethodsBoth intact and c‐terminal FGF23 were measured in plasma using commercial assays for a sub‐cohort of 295...
ObjectivesAntiretroviral interruption is associated with liver fibrosis progression in HIV/hepatitis C virus (HCV) coinfection. It is not known what level of HIV viraemia affects fibrosis progression.
MethodsWe evaluated 288 HIV/HCV‐coinfected cohort participants with undetectable HIV RNA (< 50 HIV‐1 RNA copies/mL) on two consecutive visits while on combination antiretroviral therapy (cART) without...
ObjectivesHepatitis C virus (HCV) has emerged as an important health problem in the era of effective HIV treatment. However, very few data exist on the health status and disease burden of HIV/HCV‐coinfected Canadians.
MethodsHIV/HCV‐coinfected patients were enrolled prospectively in a multicentre cohort from 16 centres across Canada between 2003 and 2010 and followed every 6 months. We determined...
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