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The cover image is based on the Research Article A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin by Indira Mendez‐David et al., https://doi.org/10.1002/hipo.23568. Image Credit: Indira Mendez‐David, Denis Joseph David, and René Hen.
We investigated the mechanisms underlying the effects of the antidepressant fluoxetine on behavior and adult hippocampal neurogenesis (AHN). After confirming our earlier report that the signaling molecule β‐arrestin‐2 (β‐Arr2) is required for the antidepressant‐like effects of fluoxetine, we found that the effects of fluoxetine on proliferation of neural progenitors and survival of adult‐born granule...
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