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Little is known about the frequency and function of CD16 + CD14 − monocytes from chronic HCV patients. We observed that the absolute numbers and ratio of CD16 + CD14 − to CD14 + CD16 − monocytes were similar between chronic HCV patients and healthy individuals. Functionally, we found that CD16 + CD14 − monocytes are more responsive to...
Weak hepatitis C virus (HCV) specific immunity in peripheral blood has been shown to be partially controlled by regulatory T cells (Treg). However, little is known about Treg present in livers of HCV-infected patients, their association with clinical parameters, and immunopathology resulting in disease progression.The frequency and phenotype of CD4+FoxP3+ Treg, conventional CD4+ T cells, and the distribution...
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