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Stem cells are known for their capacity to self‐renew and differentiate into at least one specialized cell type. Mesenchymal stem cells (MSCs) were isolated initially from bone marrow but are now known to exist in all vascularized organ or tissue in adults. MSCs are particularly relevant for therapy due to their simplicity of isolation and cultivation. The International Society for Cellular Therapy...
Subcellular Ca2+ signals control a variety of responses in the liver. For example, mitochondrial Ca2+ (Ca) regulates apoptosis, whereas Ca2+ in the nucleus regulates cell proliferation. Because apoptosis and cell growth can be related, we investigated whether Ca also affects liver regeneration. The Ca2+‐buffering protein parvalbumin, which was targeted to the mitochondrial matrix and fused...
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