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Staphylococcus lugdunensis is a human skin commensal organism, but it is considered as a virulent Staphylococcus species. In a previous study, we described the first S. lugdunensis autolysin, AtlL. This enzyme displays two enzymatic domains and generates two peptidoglycan hydrolases, an N‐acetylmuramoyl‐l‐alanine amidase and an N‐acetylglucosaminidase. In this study, to further investigate the functions...
Marlinghaus L, Becker K, Korte M, Neumann S, Gatermann SG, Szabados F. Construction and characterization of three knockout mutants of the fbl gene in Staphylococcus lugdunensis. APMIS 2011
Staphylococcus lugdunensis is an important human pathogen that causes infectious diseases similar to those caused by Staphylococcus aureus. In contrast to S. aureus, only a very few pathogenicity factors...
For several Staphylococci, such as Staphylococcus aureus, Staphylococcus saprophyticus, and Staphylococcus epidermidis, invasion of eukaryotic cells has been described and this mechanism has been considered an important part of the infection process. The fibrinogen‐binding protein (Fbl) of Staphylococcus lugdunensis, a homolog of the clumping factor A of S. aureus, has been described as fibrinogen‐binding...
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