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Aim
To compare treatment persistence in patients with type 2 diabetes initiating the glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) dulaglutide, exenatide once‐weekly (QW), liraglutide or lixisenatide in routine clinical practice in Sweden and assess clinical outcomes.
Materials and Methods
We performed a retrospective study using data from several nationwide Swedish health registries, including...
Pig liver microsomes were found to catalyze the 7α-hydroxylation of several potential bile acid precursors besides cholesterol. 26-Hydroxycholesterol, 3β-hydroxy-5-cholestenoic acid and 3β-hydroxy-5-cholenoic acid were all efficiently converted into the 7α-hydroxylated products. Two cytochrome P-450 fractions showing 7α-hydroxylase activity could be isolated. One fraction catalyzed 7α-hydroxylation...
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