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Objectives
Besides its role in regulating phosphatidylinositol‐3 kinase (PI3K) signalling in the cytosol, PTEN also has a nuclear function. In this study, we attempted to understand the mechanism of chromatin PTEN in suppressing chromosomal instability during cell division.
Materials and methods
Immunocoprecipitation, ectopic expression, and deletional analyses were used to identify the physical...