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We examined the deformation behavior of a red blood cell (RBC) in various flow fields to determine whether the extent of RBC deformation is correlated with the shear stress used as a hemolysis index. The RBC model was introduced to a simple shear flow (Couette flow) and to slightly complex flows (unsteady shear flows and stenosed flows). The RBC deformation was assessed by the maximum first principal...
We developed a mechanical model of a red blood cell (RBC) that is capable of expressing its characteristic behaviors in shear flows. The RBC was modeled as a closed shell membrane consisting of spring networks in the framework of the energy minimum concept. The fluid forces acting on RBCs were modeled from Newton's viscosity law and the conservation of momentum. In a steady shear flow, the RBC model...
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