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Purpose Thyrotropin receptor (TSHR) autoantibodies (TRAbs) are a hallmark of Graves’ disease (GD). The aim of this study was to evaluate the diagnostic accuracy of a new third generation automatic fluorescence enzyme immunoassay for TRAb measurement in GD, in comparison with two current IMAs. Methods Sera of 439 subjects (57 patients with untreated GD, 34 with treated GD, 15 with GD and Graves’...
Background Using recombinant human monoclonal thyroglobulin antibodies expressed as Fab molecules (TgAb‐Fab), we have recently confirmed the restriction of Tg epitopes in Hashimoto’s thyroiditis (HT).
Objective To investigate Tg epitopes of serum TgAb in HT adults and HT juveniles from a geographically isolated area (Sardinia).
Design and Patients Serum TgAb of 39 Sardinian HT adults, 53 Sardinian...
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