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Epigenetic effects of anti‐psychotic medications are poorly understood. We have appropriated a model whereby heterochromatin is established through 24‐ or 48‐h lipopolysaccharide (LPS) treatment, and tested the epigenetic effects of risperidone along the adenylyl cyclase/protein kinase A (AC/PKA) pathway in human liposarcoma cells that express the LPS‐sensitive Toll‐like receptor (TLR)‐4. Human SW872...