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BackgroundSeveral randomized clinical trials have compared laparoscopic cholecystectomy (LC) and small‐incision open cholecystectomy (SIOC). Most have had wide exclusion criteria and none was expertise‐based. The aim of this expertise‐based randomized trial was to compare healthcare costs, quality of life (QoL), pain and clinical outcomes after LC and SIOC.
MethodsPatients scheduled for cholecystectomy were randomized to treatment by one of two teams of surgeons with a preference for either LC or SIOC. Each team performed their specific method (SIOC or LC) as a first‐choice operation, but converted to open cholecystectomy and common bile duct exploration when necessary. Intraoperative cholangiography was carried out routinely. The intention was to include all patients undergoing cholecystectomy, including emergency operations and procedures involving surgical training for residents...