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In 2006, Shinya Yamanaka and colleagues discovered how to reprogram terminally differentiated somatic cells to a pluripotent stem cell state. The resulting induced pluripotent stem cells (iPSCs) made a paradigm shift in the field, further nailing down the disproval of the long‐held dogma that differentiation is unidirectional. The prospect of using iPSCs for patient‐specific cell‐based therapies has...
Cannabinoids are widely abused drugs. Our goal was to identify genes modulated by Δ 9 -tetrahydrocannabinol (Δ 9 -THC) treatment. We found that chronic administration of Δ 9 -THC (1.5 mg/kg/day, i.p.; 7 days) to rats, downregulates the expression of oxytocin-neurophysin (OT-NP) mRNA and of OT and oxytocin-associated NP (NP OT ) immunoreactivity in nucleus accumbens...
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