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The variable region of camelid heavy‐chain antibodies produces the smallest known antibody fragment with antigen‐binding capability (a VHH). The VHH R303 binds internalin B (InlB), a virulence factor expressed by the pathogen Listeria monocytogenes. InlB is critical for initiation of Listeria infection, as it binds a receptor (c‐Met) on epithelial cells, triggering the entry of bacteria into host...
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