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Inflammation acts as an alarming signal for the progression of various biological complications. Various reports in the literature have revealed that heterocycle‐containing synthetic compounds have a restorative capability against acute and chronic inflammatory stages. In the current study, we synthesized a series of 1,2,4‐triazole‐conjugated 1,3,4‐thiadiazole hybrid scaffolds and evaluated their...
The present research focused on designing a quinazoline skeleton, framed via 1,3,5‐triazine derivatives (QBT) through field mapping and alignment studies. The QBT derivatives were synthesized via time‐ and cost‐effective protocol. The 3D‐QSAR study, computational physicochemical properties, and ADME calculation of the derivatives were performed to establish the affinity towards the biological system...
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