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Background
Proton pump inhibitors (PPI) have no effect on non‐acid reflux events which can continue to provoke gastro‐oesophageal reflux disease (GERD) symptoms. Baclofen, a γ‐aminobutyric acid agonist, can decrease non‐acid reflux but its symptomatic benefit in refractory GERD symptoms is understudied.
Aims
To assess the efficacy of baclofen 10 mg t.i.d. vs placebo as add‐on therapy in PPI‐refractory...
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