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Aim
This study sought to determine the role of free radicals derived from mitochondria in the vasculature in the recognized age‐related endothelial dysfunction of human skeletal muscle feed arteries (SMFAs).
Methods
A total of 44 SMFAs were studied with and without acute exposure to the mitochondria‐targeted antioxidant MitoQ and nitric oxide synthase (NOS) blockade. The relative abundance of proteins...
AimRecently, it has been recognized that human skeletal muscle feed arteries can be harvested during exploratory surgery for melanoma. This approach provides vessels for in vitro study from a wide spectrum of relatively healthy humans. Although, the regulatory role of skeletal muscle feed arteries in rodent models has been documented, whether such vessels in humans possess this functionality is unknown...
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