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Purpose
Congenital stationary night blindness (CSNB) is a heterogeneous group of Mendelian retinal disorders that present in childhood. Biallelic variants altering the protein‐coding region of the TRPM1 gene are one of the commonest causes of CSNB. Here, we report the clinical and genetic findings in 10 unrelated individuals with TRPM1‐retinopathy.
Methods
Study subjects were recruited through...
Big data applications (e.g., Extract, Transform, and Load (ETL) applications) are designed to handle great volumes of data. However, processing such great volumes of data is time-consuming. There is a need to construct small yet effective test data sets during agile development of big data applications. In this paper, we apply a combinatorial test data generation approach to two real-world ETL applications...
Suanzaorenhehuan Formula (SHF) is a Chinese herbal formula for the treatment of depression-like disorders. It contains four herbs: Semen Ziziphi spinosae, Cortex Albiziae, Radix Paeoniae Alba and Semen Platycladi. The present study is to investigate the antidepressant-like effect of the ethanolic extract of SHF and its possible mechanisms.Mouse models of depression including the tail suspension test...
According to the character of certain missile power system zero-failure data, this paper presented Bayesian estimation method of zero-failure under entropy error loss. Firstly, we discussed Bayesian estimation of fixed-time censored data. Secondly, we obtained Bayesian estimation of zero-failure data by considering zero-failure data as the result of fixed-time censored test one by one. Using correlative...
The present study was undertaken to investigate the antidepressant potential of total alkaloids isolated from Semen Zizyphi Sponosae (TAS) and its possible mechanisms Mouse models of depression including the forced swimming test (FST) and the tail suspension test (TST) were used to evaluate the effects of TAS. A possible mechanism was explored in the test of antagonism of reserpine-induced hypothermia...
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