Search results for: Annalisa Zoppi

Items from 1 to 20 out of 58 results

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Diazepam as an oral hypnotic increases nocturnal blood pressure in the elderly

Roberto Fogari, Alfredo Costa, Annalisa Zoppi, Angela D’Angelo, more

Aging Clinical and Experimental Research > 2019 > 31 > 4 > 463-468

Background No study has evaluated the cardiovascular effects of diazepam in elderly subjects that assume diazepam to induce sleep. Purpose The present study was carried out in order to evaluate the effects of chronic administration of diazepam as hypnotic drug on blood pressure (BP) and heart rate (HR) in healthy elderly subjects. Patients and methods Healthy, elderly subjects, aged 65–74 years,...

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Effect of flunitrazepam as an oral hypnotic on 24-hour blood pressure in healthy volunteers

Daniele Bosone, Roberto Fogari, Annalisa Zoppi, Angela D’Angelo, more

European Journal of Clinical Pharmacology > 2018 > 74 > 8 > 995-1000

Purpose The present study was carried out in order to assess the effects of chronic administration of flunitrazepam (as an oral hypnotic) on 24-h blood pressure (BP) and heart rate (HR) in healthy young adults. Materials and methods Following a 2-week placebo run-in period, 28 healthy volunteers (13 males and 15 females) between 21 and 30 years were randomized to receive either flunitrazepam 1 mg...

article

Ambulatory 24-h ECG monitoring and cardiovascular autonomic assessment for the screening of silent myocardial ischemia in elderly type 2 diabetic hypertensive patients

Daniele Bosone, Roberto Fogari, Matteo Cotta Ramusino, Natascia Ghiotto, more

Heart and Vessels > 2017 > 32 > 5 > 507-513

The aim of the study was to evaluate the usefulness of Holter monitoring for the detection of silent myocardial ischemia (SMI) in elderly type 2 diabetic patients with hypertension and the possible relationship between SMI and cardiovascular autonomic neuropathy (CAN). Two hundred and forty-three asymptomatic outpatients, aged 65–75 years, with type 2 diabetes and essential hypertension underwent...

article

Twenty-four-hour blood pressure profile, orthostatic hypotension, and cardiac dysautonomia in elderly type 2 diabetic hypertensive patients

Alfredo Costa, Daniele Bosone, Matteo Cotta Ramusino, Natascia Ghiotto, more

Clinical Autonomic Research > 2016 > 26 > 6 > 433-439

Purpose The aim of this study was to evaluate the relationship between orthostatic hypotension (OH), defined as a decrease in systolic blood pressure (SBP) ≥20 mmHg and/or a decrease in diastolic blood pressure (DBP) ≥10 mmHg, and 24-h ambulatory BP profile in elderly hypertensive type 2 diabetic patients. Methods After a 2-week antihypertensive wash-out period, 200 hypertensive well-controlled...

article

ALISKIREN REDUCES QT DISPERSION IN HYPERTENSIVE DIABETIC PATIENTS

Roberto Fogari, Amedeo Mugellini, Pierangelo Lazzari, Gianluigi Marasi, more

Journal of the American College of Cardiology > 2011 > 57 > 14(S) > E1934

article

Difference in incidence of cough induced by imidapril and ramipril: Role of prostaglandin synthesis inhibition

Roberto Fogari, Annalisa Zoppi, Amedeo Mugellini, Maurizio Destro, more

Biomedicine & Aging Pathology > 2011 > 1 > 2 > 73-77

Aim of this study was to evaluate whether treatment with imidapril reduced cough induced by ramipril. The effect of adding indomethacin, a known inhibitor of prostaglandin (PG) synthesis, to the two ACE-inhibitors (ACE-I) on cough frequency and intensity was also assessed. After a 2-week placebo period, 97 hypertensive patients who developed cough during ramipril treatment were randomized to ramipril...

article

Effect of valsartan or olmesartan addition to amlodipine on ankle edema in hypertensive patients

Roberto Fogari, Gian Malamani, Luca Corradi, Amedeo Mugellini, more

Advances in Therapy > 2010 > 27 > 1 > 48-55

Introduction The objective of this study was to compare the effect on ankle edema of adding valsartan (V) or olmesartan (O) to amlodipine (A) in the treatment of hypertension. Methods After a 4-week placebo period, 74 adult outpatients with essential hypertension (diastolic blood pressure [DBP] >90 and <110 mmHg, and systolic blood pressure [SBP] >140 mmHg) were treated with A 10 mg once...

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Efficacy and safety of two treatment combinations of hypertension in very elderly patients

Roberto Fogari, Annalisa Zoppi, Amedeo Mugellini, Luca Corradi, more

Archives of Gerontology and Geriatrics > 2009 > 48 > 3 > 401-405

The study compared valsartan/amlodipine combination with irbesartan/hydrochlorothiazide (HCTZ) combination in very elderly hypertensives. After a 4-week placebo period, 94 hypertensives, aged 75–89 years were randomized to valsartan 160mg/amlodipine 5mg or irbesartan 300mg/HCTZ 12.5mg for 24 weeks according to a prospective, parallel group study. After 4 weeks amlodipine or HCTZ was doubled in non-responders...

article

Effectiveness of hydrochlorothiazide in combination with telmisartan and olmesartan in adults with moderate hypertension not controlled with monotherapy: a prospective, randomized, open-label, blinded end point (PROBE), parallel-arm study

Roberto Fogari, Annalisa Zoppi, Amedeo Mugellini, Paola Preti, more

Current Therapeutic Research > 2008 > 69 > 1 > 1-15

Background:The potential combinations of antihypertensive agents are many, and making rational choices depends on the characteristics of each drug and on their complementary mechanisms of action.Objective: The aim of this study was to evaluate the effectiveness of adding hydrochlorothiazide (HCTZ) 12.5 mg to olmesartan 20 mg or telmisartan 80 mg on blood pressure (BP) in patients with moderate hypertension...

article

Addition of Manidipine Improves the Antiproteinuric Effect of Candesartan in Hypertensive Patients With Type II Diabetes and Microalbuminuria

Roberto Fogari, Luca Corradi, Annalisa Zoppi, Pierangelo Lazzari, more

American Journal of Hypertension > 2007 > 20 > 10 > 1092-1096

We sought to compare the effect of manidipine versus hydrochlorothiazide (HCTZ) in addition to candesartan on the urinary albumin excretion rate (UAER) in hypertensive patients with type II diabetes and microalbuminuria.After a 2-week washout and run-in period, and 8-week monotherapy with candesartan 16 mg every day, 174 microalbuminuric diabetic hypertensive patients with uncontrolled blood pressure...

article

Effect of Telmisartan–Amlodipine Combination at Different Doses on Urinary Albumin Excretion in Hypertensive Diabetic Patients With Microalbuminuria

Roberto Fogari, Giuseppe Derosa, Annalisa Zoppi, Paola Preti, more

American Journal of Hypertension > 2007 > 20 > 4 > 417-422

Aim of this study was to evaluate the effect of the telmisartan–amlodipine combination at different doses on urinary albumin excretion rate (UAER) in hypertensive diabetic patients with microalbuminuria.After a 2-week placebo period, 300 hypertensive patients with type 2 diabetes and microalbuminuria were treated with the 40 mg of telmisartan and 2.5 mg of amlodipine combination. After 4 weeks 210...

article

Effect on the development of ankle edema of adding delapril to manidipine in patients with mild to moderate essential hypertension: A three-way crossover study

Roberto Fogari, GianDomenico Malamani, Annalisa Zoppi, Amedeo Mugellini, more

Clinical Therapeutics > 2007 > 29 > 3 > 413-418

Use of the combination of an angiotensinconverting enzyme inhibitor (ACEI) and a calcium channel blocker (CCB) is considered a rational approach in patients whose hypertension is not controlled by monotherapy, providing better blood pressure (BP) control than the individual components with a lower incidence of adverse effects. In particular, such combinations have been found to reduce the incidence...

article

Impact of Dual Calcium Channel and Renin-Angiotensin System Blockade

Roberto Fogari, Annalisa Zoppi

American Journal of Hypertension > 2006 > 19 > 12 > 1293-1299

Impaired fibrinolytic function, characterized by increased plasminogen activator inhibitor type 1 (PAI-1) levels and decreased tissue plasminogen activator (t-PA) activity, has been found in patients with hypertension and may account in part for the increased risk of atherosclerosis and its clinical complications in these patients. Failure to correct this prothrombotic state may be one of the possible...

article

Effects of amlodipine-atorvastatin combination on inflammation markers and insulin sensitivity in normocholesterolemic obese hypertensive patients

Roberto Fogari, Paola Preti, Annalisa Zoppi, Pierangelo Lazzari, more

European Journal of Clinical Pharmacology > 2006 > 62 > 10 > 817-822

Objective The objective of this study was to assess the effect of amlodipine-atorvastatin combination on plasma interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and insulin sensitivity in normocholesterolemic obese hypertensive patients. Materials and methods After a 4-week placebo wash-out period, 50 normocholesterolemic [total cholesterol (TC) <5.2 mmol/L], obese (BMI ≥30 kg/m²) hypertensive...

article

Effect of Telmisartan/Hydrochlorothiazide Combination Versus Nifedipine GITS on Ambulatory Blood Pressure and Sympathetic Activation

Roberto Fogari, Paola Preti, Annalisa Zoppi, Luca Corradi, more

American Journal of Hypertension > 2005 > 18 > 5 > 577-583

This study compares the effects of telmisartan hydrochlorothiazide (HCTZ) combination versus nifedipine GITS on ambulatory blood pressure (BP) and sympathetic activity, in patients with mild-to-moderate hypertension. One hundred twenty-four outpatients with sitting diastolic BP ≥95 mm Hg and <110 mm Hg were randomized to telmisartan 80 mg/HCTZ 12.5 mg daily (n = 62) or nifedipine GITS 60 mg...

article

Influence of telmisartan hydrochlorothiazide combination on cognitive function in elderly hypertensive patients

Roberto Fogari, Amedeo Mugellini, Luca Corradi, Maurizio Destro, more

American Journal of Hypertension > 2005 > 18 > 5 Supplement > A58

article

Effect of valsartan on adiponectine, leptin and resistine in hypertensive obese patients

Roberto Fogari, Giuseppe Derosa, Amedeo Mugellini, Paola Preti, more

American Journal of Hypertension > 2005 > 18 > 5 Supplement > A196-A197

article

Is the Effect of Antihypertensive Drugs on Platelet Aggregability and Fibrinolysis Clinically Relevant?

Roberto Fogari, Annalisa Zoppi

American Journal of Cardiovascular Drugs > 2005 > 5 > 4 > 211-223

Hypertension is associated with decreased fibrinolytic potential, mainly expressed as elevated plasma plasminogen activator inhibitor type 1 (PAI-1) levels, and increased platelet aggregability, which may account in part for the increased risk of atherosclerosis and its clinical complications in hypertensive patients. The effects of antihypertensive drugs on this prothrombotic state have been investigated...

article

Effect of successful hypertension control by manidipine or lisinopril on albuminuria and left ventricular mass in diabetic hypertensive patients with microalbuminuria

Roberto Fogari, Amedeo Mugellini, Annalisa Zoppi, Pierangelo Lazzari, more

European Journal of Clinical Pharmacology > 2005 > 61 > 7 > 483-490

ObjectiveThe aim of this open-labelled, randomised, parallel-group study was to evaluate the effect of long-term monotherapy with manidipine or lisinopril on albumin excretion rate (AER) and left ventricular mass index (LVMI) in hypertensive patients with type-2 diabetes and microalbuminuria.Methods After a 4-week wash-out period, 174 patients with essential hypertension [diastolic blood pressure...

article

Effect of amlodipine–atorvastatin combination on fibrinolysis in hypertensive hypercholesterolemic patients with insulin resistance

Roberto Fogari, Giuseppe Derosa, Pierangelo Lazzari, Annalisa Zoppi, more

American Journal of Hypertension > 2004 > 17 > 9 > 823-827

The aim of this study was to evaluate the effect of the amlodipine–atorvastatin combination on plasma tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) activity in hypercholesterolemic, hypertensive patients with insulin resistance. The study population included 45 patients, aged 41 to 70 years, with mild to moderate essential hypertension (diastolic blood pressure...

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Search results for: Annalisa Zoppi

Diazepam as an oral hypnotic increases nocturnal blood pressure in the elderly

Effect of flunitrazepam as an oral hypnotic on 24-hour blood pressure in healthy volunteers

Ambulatory 24-h ECG monitoring and cardiovascular autonomic assessment for the screening of silent myocardial ischemia in elderly type 2 diabetic hypertensive patients

Twenty-four-hour blood pressure profile, orthostatic hypotension, and cardiac dysautonomia in elderly type 2 diabetic hypertensive patients

ALISKIREN REDUCES QT DISPERSION IN HYPERTENSIVE DIABETIC PATIENTS

Difference in incidence of cough induced by imidapril and ramipril: Role of prostaglandin synthesis inhibition

Effect of valsartan or olmesartan addition to amlodipine on ankle edema in hypertensive patients

Efficacy and safety of two treatment combinations of hypertension in very elderly patients

Effectiveness of hydrochlorothiazide in combination with telmisartan and olmesartan in adults with moderate hypertension not controlled with monotherapy: a prospective, randomized, open-label, blinded end point (PROBE), parallel-arm study

Addition of Manidipine Improves the Antiproteinuric Effect of Candesartan in Hypertensive Patients With Type II Diabetes and Microalbuminuria

Effect of Telmisartan–Amlodipine Combination at Different Doses on Urinary Albumin Excretion in Hypertensive Diabetic Patients With Microalbuminuria

Effect on the development of ankle edema of adding delapril to manidipine in patients with mild to moderate essential hypertension: A three-way crossover study

Impact of Dual Calcium Channel and Renin-Angiotensin System Blockade

Effects of amlodipine-atorvastatin combination on inflammation markers and insulin sensitivity in normocholesterolemic obese hypertensive patients

Effect of Telmisartan/Hydrochlorothiazide Combination Versus Nifedipine GITS on Ambulatory Blood Pressure and Sympathetic Activation

Influence of telmisartan hydrochlorothiazide combination on cognitive function in elderly hypertensive patients

Effect of valsartan on adiponectine, leptin and resistine in hypertensive obese patients

Is the Effect of Antihypertensive Drugs on Platelet Aggregability and Fibrinolysis Clinically Relevant?

Effect of successful hypertension control by manidipine or lisinopril on albuminuria and left ventricular mass in diabetic hypertensive patients with microalbuminuria

Effect of amlodipine–atorvastatin combination on fibrinolysis in hypertensive hypercholesterolemic patients with insulin resistance

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