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Der Riesenzelltumor ist ein primrer Knochentumor von intermedirer Dignitt. Die Vorhersage des biologischen Verhaltens und des Krankheitsverlaufs ist nach konventionellen histologischen Diagnosemanahmen kaum mglich. Anhand einer Fallbeschreibung einer malignen Entartung eines Riesenzelltumors am distalen Radius wird die Mglichkeit und die Bedeutung der DNS-Zytophotometrie dargestellt. Mit Hilfe dieses...
AbstractWe studied DNA ploidy by smear cytophotometry and proliferation activity by Ki-67 MIB immunohistochemistry in 69 primary and recurrent giant cell tumors (GCT) from 50 randomly selected patients. The obtained results were evaluated with comparisons made to the available clinical data. From the 46 primary tumors 63% showed diploidy and 37% aneuploidy. A significantly (P=0.026) higher recurrence...
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