Search results for: Yongsoo Kim

Items from 1 to 20 out of 49 results

article

2D shear wave liver elastography by Aixplorer to detect portal hypertension in cirrhosis: An individual patient data meta‐analysis

Maja Thiele, Mie B. Hugger, Yongsoo Kim, Pierre‐Emmanuel Rautou, more

Liver International > 40 > 6 > 1435 - 1446

Background & Aims Liver stiffness measured with 2‐dimensional shear wave elastography by Supersonic Imagine (2DSWE‐SSI) is well‐established for fibrosis diagnostics, but non‐conclusive for portal hypertension. Methods We performed an individual patient data meta‐analysis of 2DSWE‐SSI to identify clinically significant portal hypertension (CSPH), severe portal hypertension and large varices...

article

GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice

Lisette M. Cornelissen, Roebi Bruijn, Linda Henneman, Yongsoo Kim, more

Journal of Mammary Gland Biology and Neoplasia > 2019 > 24 > 3 > 271-284

Heterozygous mutations in the transcription factor GATA3 are identified in 10–15% of all breast cancer cases. Most of these are protein-truncating mutations, concentrated within or downstream of the second GATA-type zinc-finger domain. Here, we investigated the functional consequences of expression of two truncated GATA3 mutants, in vitro in breast cancer cell lines and in vivo in the mouse mammary...

article

Investigation of postoperative hypernasality after superiorly based posterior pharyngeal flap

Yu-Jeong Shin, Yongsoo Kim

Maxillofacial Plastic and Reconstructive Surgery > 2018 > 40 > 1 > 1-6

Background Velopharyngeal insufficiency that accompanies speech resonance and articulation disorders can be managed through several intervention methods such as speech-language therapy, prosthetic aids, and surgery. However, for patients with severe hypernasality, surgical interventions are highly recommended. Among available surgical techniques, the posterior pharyngeal flap is most common. Case...

article

Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism

Duco Steven Koenis, Lejla Medzikovic, Pieter Bas van Loenen, Michel van Weeghel, more

Cell Reports > 2018 > 24 > 8 > 2127-2140.e7

Activation of macrophages by inflammatory stimuli induces reprogramming of mitochondrial metabolism to support the production of pro-inflammatory cytokines and nitric oxide. Hallmarks of this metabolic rewiring are downregulation of α-ketoglutarate formation by isocitrate dehydrogenase (IDH) and accumulation of glutamine-derived succinate, which enhances the inflammatory response via the activity...

article

Radial Glial Lineage Progression and Differential Intermediate Progenitor Amplification Underlie Striatal Compartments and Circuit Organization

Sean M. Kelly, Ricardo Raudales, Miao He, Jannifer H. Lee, more

Neuron > 2018 > 99 > 2 > 345-361.e4

The circuitry of the striatum is characterized by two organizational plans: the division into striosome and matrix compartments, thought to mediate evaluation and action, and the direct and indirect pathways, thought to promote or suppress behavior. The developmental origins of these organizations and their developmental relationships are unknown, leaving a conceptual gap in understanding the cortico-basal...

article

Prediction of mycotoxin risks due to climate change in Korea

Ho-Sung Lee, Nam Ji Kwon, Yongsoo Kim, Hunjoo Lee

Applied Biological Chemistry > 2018 > 61 > 4 > 389-396

Climate change has been considered as a main threat for food safety by influencing on crop production and food supply chain through the change in temperature and humidity. To prevent risks of mycotoxins from climate change, it is important to predict mycotoxin risks with statistical approaches and stepwise process to compile large volume of datasets, such as climate change, contamination level, and...

article

Brain-wide Maps Reveal Stereotyped Cell-Type-Based Cortical Architecture and Subcortical Sexual Dimorphism

Yongsoo Kim, Guangyu Robert Yang, Kith Pradhan, Kannan Umadevi Venkataraju, more

Cell > 2017 > 171 > 2 > 456-469.e22

The stereotyped features of neuronal circuits are those most likely to explain the remarkable capacity of the brain to process information and govern behaviors, yet it has not been possible to comprehensively quantify neuronal distributions across animals or genders due to the size and complexity of the mammalian brain. Here we apply our quantitative brain-wide (qBrain) mapping platform to document...

article

Korean Rural Development Administration's web based food and nutrient database management and validation system (NutriManager) – A report

Hunjoo Lee, Eunyoung Han, Nam ji Kwon, Yongsoo Kim, more

Journal of Food Composition and Analysis > 2017 > 62 > C > 231-238

Food composition databases (FCDBs) are important to studies, industries, polices, and modeling related to diet and food. A FCDB has been provided by each country’s government organizations. In Korea, the FCDB has been produced and provided by the Rural Development Administration (RDA) and the national food analysis system (NFAS), a network between qualified laboratories by the nation. In this study,...

article

The comparative study of resonance disorders for Vietnamese and Korean cleft palate speakers using nasometer

Yu-Jeong Shin, Yongsoo Kim, Hyun-Gi Kim

Maxillofacial Plastic and Reconstructive Surgery > 2017 > 39 > 1 > 1-5

Background Nasalance is used to evaluate the velopharyngeal incompetence in clinical diagnoses using a nasometer. The aim of this study is to find the nasalance differences between Vietnamese cleft palate children and Korean cleft palate children by measuring the nasalance of five oral vowels. Methods Ten Vietnamese cleft palate children after surgery, three Vietnamese children for the control group,...

article

How many times should we repeat measuring liver stiffness using shear wave elastography?: 5-repetition versus 10-repetition protocols

Seung Hee Choi, Woo Kyoung Jeong, Yongsoo Kim, Sanghyeok Lim, more

Ultrasonics > 2016 > 72 > C > 158-164

The purpose of this study is to evaluate whether a 5-repetition liver stiffness (LS) measurement as the standard protocol of shear wave elastography (SWE) is comparable to a conventional 10-repetition measurement protocol and to identify factors that influence the reliability of the 5-repetition protocol. A total of 346 patients (mean, 48.0years; range, 15–81years, M:F=192:154) who underwent SWE were...

article

Utility of sodium tetradecyl sulfate sclerotherapy from benign oral vascular lesion

Bo-Eun Choi, Yongsoo Kim, Dae-Ho Leem, Jin-A Baek, more

Maxillofacial Plastic and Reconstructive Surgery > 2016 > 38 > 1 > 1-4

Background Hemangioma and vascular malformation are benign vascular lesions that often occur in cephalic and cervical region. Currently, surgical resection, laser therapy, angiographic embolization, use of steroids, and sclerotherapy are used as treatments. Case presentation This study reports three cases of benign vascular lesions that are remarkably treated by sodium tetradecyl sulfate (STS) injection,...

chapter

Applying Hybrid Neural Fuzzy System to Embedded System Hardware/Software Partitioning

Yue Huang, YongSoo Kim

Lecture Notes in Computer Science > Advanced Intelligent Computing Theories and Applications. With Aspects of Artificial Intelligence > Fuzzy Systems and Soft Computing > 660-669

Hardware/Software (HW/SW) partitioning is becoming an increasingly crucial step in embedded system co-design. To cope with roughly assumed parameters in system specification and imprecise benchmarks for judging the solution’s quality, researchers have been trying to find methods for a semi-optimal partitioning scheme in HW/SW partitioning for years. This paper proposes an application of a hybrid neural...

article

Strategies and Tools for Combinatorial Targeting of GABAergic Neurons in Mouse Cerebral Cortex

Miao He, Jason Tucciarone, SooHyun Lee, Maximiliano José Nigro, more

Neuron > 2016 > 92 > 2 > 555

article

Strategies and Tools for Combinatorial Targeting of GABAergic Neurons in Mouse Cerebral Cortex

Miao He, Jason Tucciarone, SooHyun Lee, Maximiliano José Nigro, more

Neuron > 2016 > 91 > 6 > 1228-1243

Systematic genetic access to GABAergic cell types will facilitate studying the function and development of inhibitory circuitry. However, single gene-driven recombinase lines mark relatively broad and heterogeneous cell populations. Although intersectional approaches improve precision, it remains unclear whether they can capture cell types defined by multiple features. Here we demonstrate that combinatorial...

article

Diagnosis of Clinically Significant Portal Hypertension in Patients with Cirrhosis: Splenic Arterial Resistive Index versus Liver Stiffness Measurement

Chul-min Lee, Woo Kyoung Jeong, Sanghyeok Lim, Yongsoo Kim, more

Ultrasound in Medicine & Biology > 2016 > 42 > 6 > 1312-1320

The purpose of the present study is to compare the diagnostic accuracy of the splenic arterial resistive index (SARI) with that of liver stiffness measurement (LSM) for identifying patients with clinically significant portal hypertension (CSPH). We included 47 patients (M:F = 37:10) who underwent Doppler ultrasonography, LSM and hepatic venous pressure gradient (HVPG) on the same day. We investigated...

chapter

8.7 Physically unclonable function for secure key generation with a key error rate of 2E-38 in 45nm smart-card chips

Bohdan Karpinskyy, Yongki Lee, Yunhyeok Choi, Yongsoo Kim, more

2016 IEEE International Solid-State Circuits Conference (ISSCC) > 158 - 160

2016 IEEE International Solid-State Circuits Conference (ISSCC)

Physically unclonable function (PUF) circuits are for generating unique secure keys or chip IDs based on intrinsic properties of each chip itself [1–2]. PUFs are a step forward to improve the security level compared to traditional NVM (non-volatile memory) solutions (FUSEs, EEPROM/FLASH, etc.) because they resolve security issues, such as active data-probing, transferring the security key from outside,...

article

Modeling and response time analysis of the Level 2 system for a continuous steel casting process

Yongsoo Kim, Cheeha Kim

Control Engineering Practice > 2015 > 44 > C > 117-125

When a process control system (PCS) is designed or improved, it is very desirable to check in advance whether it responds within time constraints because correcting a system after implementation requires time and effort. A PCS processes bursty messages from programmable logic controllers. The response time to each individual message is different from one another, so it must be evaluated. This paper...

article

Evaluation of portal hypertension by real‐time shear wave elastography in cirrhotic patients

Tae Yeob Kim, Woo Kyoung Jeong, Joo Hyun Sohn, Jinoo Kim, more

Liver International > 35 > 11 > 2416 - 2424

Background & AimsTo assess the correlation between liver stiffness measurement (LSM) by real‐time shear wave elastography (SWE) and hepatic venous pressure gradient (HVPG) and to investigate the diagnostic performance of SWE for predicting clinically significant and severe portal hypertension (CSPH and SPH). MethodsClinical data of 115 cirrhotic patients with haemodynamic measurement were consecutively...

article

In Vitro Assessment of the Anticancer Potential of Evodiamine in Human Oral Cancer Cell Lines

Khadka Sachita, Yongsoo Kim, Hyun‐Ju Yu, Sung‐Dae Cho, more

Phytotherapy Research > 29 > 8 > 1145 - 1151

Evodiamine, a bioactive alkaloid, has been regarded as having antioxidant, antiinflammatory, and anticancer properties. In the present study, we explored the effects of evodiamine on cell growth and apoptosis in human oral cancer cell lines. Our data revealed that evodiamine significantly inhibited the proliferation of human oral cancer cells and resulted in the cleavages of PARP (poly (ADP‐ribose)...

article

Usefulness of B‐mode and doppler sonography for the diagnosis of severe acute viral hepatitis A

Sang Wook Shin, Tae Yeob Kim, Woo Kyoung Jeong, Yongsoo Kim, more

Journal of Clinical Ultrasound > 43 > 6 > 384 - 392

BackgroundTo investigate B‐mode and Doppler ultrasonography (US) features correlating with laboratory findings for the diagnosis of severe acute hepatitis (SAH) in patients with hepatitis A virus infection. MethodsThirty‐nine consecutive serologically proven patients were enrolled. Decreased parenchymal echotexture, periportal tracking, gallbladder wall change, and splenomegaly were assessed on B‐mode...

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INFONA - science communication portal

Search results for: Yongsoo Kim

2D shear wave liver elastography by Aixplorer to detect portal hypertension in cirrhosis: An individual patient data meta‐analysis

GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice

Investigation of postoperative hypernasality after superiorly based posterior pharyngeal flap

Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism

Radial Glial Lineage Progression and Differential Intermediate Progenitor Amplification Underlie Striatal Compartments and Circuit Organization

Prediction of mycotoxin risks due to climate change in Korea

Brain-wide Maps Reveal Stereotyped Cell-Type-Based Cortical Architecture and Subcortical Sexual Dimorphism

Korean Rural Development Administration's web based food and nutrient database management and validation system (NutriManager) – A report

The comparative study of resonance disorders for Vietnamese and Korean cleft palate speakers using nasometer

How many times should we repeat measuring liver stiffness using shear wave elastography?: 5-repetition versus 10-repetition protocols

Utility of sodium tetradecyl sulfate sclerotherapy from benign oral vascular lesion

Applying Hybrid Neural Fuzzy System to Embedded System Hardware/Software Partitioning

Strategies and Tools for Combinatorial Targeting of GABAergic Neurons in Mouse Cerebral Cortex

Strategies and Tools for Combinatorial Targeting of GABAergic Neurons in Mouse Cerebral Cortex

Diagnosis of Clinically Significant Portal Hypertension in Patients with Cirrhosis: Splenic Arterial Resistive Index versus Liver Stiffness Measurement

8.7 Physically unclonable function for secure key generation with a key error rate of 2E-38 in 45nm smart-card chips

Modeling and response time analysis of the Level 2 system for a continuous steel casting process

Evaluation of portal hypertension by real‐time shear wave elastography in cirrhotic patients

In Vitro Assessment of the Anticancer Potential of Evodiamine in Human Oral Cancer Cell Lines

Usefulness of B‐mode and doppler sonography for the diagnosis of severe acute viral hepatitis A

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