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Purpose We have evaluated thoracic conformation of patients in order to derive a numeric value predictive of an increased dose to left anterior descending coronary artery (LAD), critical structure for the development of late radio induced cardiac morbidity. Methods We have evaluated 91 patients (36–88 years) affected by breast cancer stage I–II (Tis–T1–2 N0–1), undergoing adjuvant radiotherapy with...
43 patients with stage III NSCLC (non-small cell lung cancer) entered a phase II study aimed at evaluating the toxicity and the activity of a combined modality programme including an accelerated split-course schedule (type B) of thoracic radiation therapy and a combination chemotherapy with vinorelbine and carboplatin. An objective response was achieved in 1842 evaluable patients (5 complete and...
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