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Mitochondrial dysfunction is considered to be an important factor that leads to aging and premature aging diseases. Transferring mitochondria to cells is an emerging and promising technique for the therapy of mitochondrial deoxyribonucleic acid (mtDNA)‐related diseases. This paper presents a unique method of controlling the quality and quantity of mitochondria transferred to single cells using an...
Mitochondrial Transfer
In article number 2103086, Gang Li, Dong Sun, and co‐workers present a novel method of controlling the quality and quantity of mitochondria transferred to single cells using an automated optical tweezer‐based micromanipulation system. The transfer of isolated mitochondria from fetal mesenchymal stem cells (fMSCs) to adult mesenchymal stem cells (aMSCs) by the developed system...
Background Damaged endothelial cells and downregulated osteogenic ability are two key pathogenic mechanisms of glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH). Recent studies suggested that transplantation of CD34+ stem cell-derived exosomes (CD34+-Exos) can treat ischemic diseases by promoting neovascularization and that miR-26a is an important positive regulator of osteogenesis...
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