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Background Only a small number of patients survive out-of-hospital-cardiac-arrest (OHCA). The duration of CPR varies considerably and transportation of patients under CPR is often unsuccessful. Termination-of-resuscitation (TOR)-criteria aim to preclude futile resuscitation efforts.Our goal was to find out to which extent existing TOR-criteria can be transferred to paediatric OHCA-patients with special...
Mutations affecting the mitochondrial DNA‐polymerase gamma 1 (POLG1) gene have been shown to cause Alpers‐Huttenlocher disease. Ultrastructural data on brain and muscle tissue are rare. We report on ultrastructural changes in brain and muscle tissue of two sisters who were compound heterozygous for the c.2243G>C and c.1879C>T POLG1 mutations. Patient 1 (16 years) presented with epilepsia partialis...
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