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Background Lipotoxicity plays an important role in the pathogenesis of kidney injury. Our previous study demonstrated that activation of local renin-angiotensin system (RAS) was involved in saturated free fatty acids palmitic acid (PA)-induced tubular cell injuries. The current study aims to investigate whether suppression of RAS by combination of direct renin inhibitor aliskiren and noncanonical...
Molecular wires constitute the building blocks for nanoscale interconnects. However, the exponential decrease in conductance with wire length severely limits their applications. We predict, using first principles calculations, that armchair graphene nanoribbon (AGNR) wires, connected by transverse zigzag edges to wider AGNR electrodes, can exhibit anomalous resonant transmission peaks that are nearly...
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