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Background Molecular signaling of angiogenesis begins within hours after initiation of a stroke and the following regulation of endothelial integrity mediated by growth factor receptors and vascular growth factors. Recent studies further provided insights into the coordinated patterns of post-stroke gene expressions and the relationships between neurodegenerative diseases and neural function recovery...
Information processing is an important characteristic of biological neurons. Here, we proposed a method to measure the information transmission ability of neurons. Due to the nonlinear dynamics of neuron, which is experimentally verified, we have to solve the Hamilton-Jacobi inequalities (HJIs) to get the information transmission ability of neuron. Instead of directly solving HJIs, fuzzy interpolation...
Signal transduction plays an important role in biological organisms. Here, we proposed a method to access the information of the signal transduction ability of signal transduction pathway in the cells. Due to the nonlinear signal transduction pathway model, we have to solve the Hamilton-Jacobi inequalities (HJIs) to get the measurement. Instead of directly solving HJIs, fuzzy interpolation method...
Animal behavior is governed by the activity of interconnected brain circuits. Comprehensive brain wiring maps are thus needed in order to formulate hypotheses about information flow and also to guide genetic manipulations aimed at understanding how genes and circuits orchestrate complex behaviors.To assemble this map, we deconstructed the adult Drosophila brain into approximately 16,000 single neurons...
Procedures for generating the standard Drosophila brain model with coordinate information are presented. A deterministic reference template is pursued for data integration and comparison. We propose a shape-averaging algorithm for creating the standard template, including axial and non-axial structures. The standard Drosophila brain comprises the standard cortex and the standard neuropils. The standard...
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