Search results for: Jarmila Vojtíšková

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article

A novel locus on mouse chromosome 7 that influences survival after infection with tick-borne encephalitis virus

Martin Palus, Yahya Sohrabi, Karl W. Broman, Hynek Strnad, more

BMC Neuroscience > 2018 > 19 > 1 > 1-11

Background Tick-borne encephalitis (TBE) is the main tick-borne viral infection in Eurasia. Its manifestations range from inapparent infections and fevers with complete recovery to debilitating or fatal encephalitis. The basis of this heterogeneity is largely unknown, but part of this variation is likely due to host genetic. We have previously found that BALB/c mice exhibit intermediate susceptibility...

article

Mice with different susceptibility to tick-borne encephalitis virus infection show selective neutralizing antibody response and inflammatory reaction in the central nervous system

Martin Palus, Jarmila Vojtíšková, Jiří Salát, Jan Kopecký, more

Journal of Neuroinflammation > 2013 > 10 > 1 > 1-13

Background The clinical course of tick-borne encephalitis (TBE), a disease caused by TBE virus, ranges from asymptomatic or mild influenza-like infection to severe debilitating encephalitis or encephalomyelitis. Despite the medical importance of this disease, some crucial steps in the development of encephalitis remain poorly understood. In particular, the basis of the disease severity is largely...

article

Loci controlling lymphocyte production of interferon γ after alloantigen stimulation in vitro and their co-localization with genes controlling lymphocyte infiltration of tumors and tumor susceptibility

Marie Lipoldová, Helena Havelková, Jana Badalová, Jarmila Vojtíšková, more

Cancer Immunology, Immunotherapy > 2010 > 59 > 2 > 203-213

Low infiltration of lymphocytes into cancers is associated with poor prognosis, but the reasons why some patients exhibit a low and others a high infiltration of tumors are unknown. Previously we mapped four loci (Lynf1–Lynf4) controlling lymphocyte infiltration of mouse lung tumors. These loci do not encode any of the molecules that are involved in traffic of lymphocytes. Here we report a genetic...

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Keywords

ANTIBODY PRODUCTION (1)
CANDIDATE GENE (1)
CHROMOSOME 7 (1)
FLAVIVIRUS ENCEPHALITIS (1)
GENE MAPPING (1)
GENETIC CONTROL OF INTERFERON Γ PRODUCTION (1)
LYMPHOCYTE INFILTRATION OF TUMORS (1)
MOUSE MODEL (1)
NEUROINFLAMMATION (1)
SURVIVAL (1)
SUSCEPTIBILITY LOCUS (1)
TICK-BORNE ENCEPHALITIS (1)
TICK-BORNE ENCEPHALITIS VIRUS (TBEV) (1)
TUMOR SUSCEPTIBILITY (1)
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Search results for: Jarmila Vojtíšková

A novel locus on mouse chromosome 7 that influences survival after infection with tick-borne encephalitis virus

Mice with different susceptibility to tick-borne encephalitis virus infection show selective neutralizing antibody response and inflammatory reaction in the central nervous system

Loci controlling lymphocyte production of interferon γ after alloantigen stimulation in vitro and their co-localization with genes controlling lymphocyte infiltration of tumors and tumor susceptibility

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