The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Histone deacetylase inhibitors (HDIs) cause an irreversible cell cycle arrest in G1 phase and senescence of E1A + Ras transformed fibroblasts. The modulation of the antiproliferative action of the RNA synthesis inhibitor actinomycin D (AMD) with sodium butyrate (NaBut) has been studied. It is shown that NaBut enhances the cytotoxic effect of low AMD concentrations (<8 nM). However, at high concentrations...
Histone deacetylase inhibitors (HDIs) cause irreversible cell cycle arrest and senescence of transformed E1A + Ras cells. The HDI sodium butyrate (NaB) causes a violation of DNA repair and, as a consequence, phosphorylation of DNA breaks marker histone H2AX. It is shown that the Gadd45 family proteins play a role in regulation of proliferation, apoptosis, and repair. In the present work, we studied...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.