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G protein‐coupled receptor 83 (GPR83) is primarily expressed in the brain and is implicated in the regulation of energy metabolism and some anxiety‐related behaviours. Recently, the PCSK1N/proSAAS‐derived peptide PEN, the procholecystokinin‐derived peptide proCCK56‐63, and family with sequence similarity 237 member A (FAM237A) were all reported as efficient agonists of GPR83. However, these results...