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Brain white matter hyperintensities (WMHs) are linked to increased risk of cerebrovascular and neurodegenerative diseases among the elderly. Consequently, detection and characterization of WMHs are of significant clinical importance. We propose a novel approach for WMH segmentation from multi-contrast MRI where both voxel-based and lesion-based information are used to improve overall performance in...
Alzheimer’s disease is a prevalent and progressive neurodegenerative disease that often starts clinically as a memory deficit. Specifically, the hippocampal formation (HF) and medial part of the temporal lobe (MTL) are severely affected. Those structures are at the core of the neural system responsible for encoding and retrieval of the memory for facts and events (episodic memory) which is dependent...
Medial temporal lobe (MTL) is a region of the brain related with processing and declarative memory consolidation. Structural changes in this region are directly related with Alzheimer’s disease and other dementias. Manual delimitation of these structures is very time consuming and error prone. Automatic methods are needed in order to solve these problems and make it available in the clinical practice...
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