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According to epidemiologic studies, smoking appears to downregulate the prevalence of Parkinson’s disease (PD), possibly due to antiinflammatory mechanisms via activation of α7 nicotinic acetylcholine receptors (α7 nAChRs). This receptor also appears to play a role in T-cell differentiation. Recently, it has become apparent that the innate immune system participates in PD pathogenesis. The aim of...
Resting state functional magnetic resonance imaging (rs-fMRI) has been applied to investigate topographic structure in Parkinson’s disease (PD). Alteration of topographic architecture has been inconsistent in PDTo investigate the network profile of PD using graph theoretical analysis.Twenty six newly diagnosed PD and 19 age- and gender- matched healthy controls (HC) were included in our analysis....
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