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The cyanobacterium Microcystis aeruginosa is a mesophilic freshwater organism, which cannot tolerate sulphide. However, it was possible to isolate a sulphide-resistant (Sr) mutant strain that was able to survive in a normally lethal medium sulphide. In order to evaluate the cost of the mutation conferring sulphide resistance in the Sr...
Aims To identify the variables affecting vancomycin pharmacokinetics in medical ICU patients and to evaluate the potential efficacy of dosage schedules by PK/PD analysis. Design A retrospective pharmacokinetic analysis of serum levels obtained in routine vancomycin monitoring was performed. Setting A 12-bed general ICU of a university teaching hospital. Patients Forty-six vancomycin-treated...
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