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Umbelliferone, 4-methyl-umbelliferone and their farnesyloxy and geranyloxy analogues were synthesized and evaluated for their antioxidant and soybean lipoxygenase inhibitory activity as well as their cytotoxicity against human neuroblastoma cell line SK-N-SH and human hepatoma cell line HepG2. Auraptene (3), followed by 4-methyl-auraptene (4) exhibit modest cytotoxity against the HepG2 cell line....