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Abstract We show that the four high-energy Littlest Seesaw parameters in the flavour basis, namely two real Yukawa couplings plus the two right-handed neutrino masses, can be determined by an excellent fit to the seven currently constrained observables of low-energy neutrino data and leptogenesis. Taking into account renormalisation group corrections, we estimate χ2 ≃ 1.5-2.6 for the three d.o.f...