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BackgroundActivation of extracellular signal‐regulated kinases (ERK1/2) has been shown to play an important role in several pain states. Here we investigated the ERK1/2 contribution to non‐evoked and evoked pain‐like behaviour in rats after surgical incision.
MethodsSpinal phosphorylation of ERK1 and ERK2 was assessed 15 min, 4 h, 24 h and 5 days after plantar incision and sham incision. The effect...
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