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Our recent study, by up-regulation of AQP5 expression, showed enhanced proliferation and migration potential in lung cancer. However, so far none of the in vivo study of gene silencing of AQP5 has been tested. In this study, we tested roles of AQP5 on lung cancer metastasis potential by gene silencing of AQP5 in two lung cancer cell lines and tried to monitor lung metastases with EGFP marker. Lungs...