Search results for: Raphael C. Sun

Items from 1 to 15 out of 15 results

article

Impact of middle cerebral artery pulsatility index on donor survival in twin‐twin transfusion syndrome

Eyal Krispin, Alireza A. Shamshirsaz, Hiba J. Mustafa, Raphael C. Sun, more

Objective To assess outcomes in twin‐twin transfusion syndrome (TTTS) according to middle cerebral artery pulsatility index (MCA‐PI) prior to fetoscopic laser photocoagulation (FLPC) surgery. Methods A retrospective cohort analysis of monochorionic‐twin pregnancies complicated by TTTS who underwent FLPC at two fetal centers (2012–2021). The cohort was stratified according to abnormal MCA‐PI of...

article

Outcomes of laparoscopy‐assisted fetoscopic laser photocoagulation for twin–twin transfusion syndrome: An established alternative for inaccessible anterior placenta

Eyal Krispin, Ahmed A. Nassr, Jimmy Espinoza, Roopali Donepudi, more

Prenatal Diagnosis > 41 > 12 > 1582 - 1588

Objective To evaluate laparoscopy‐assisted fetoscopic laser photocoagulation (FLPC) of placental anastomoses in the treatment of twin‐to‐twin‐transfusion syndrome (TTTS). Study Design We performed a retrospective cohort study analyzing pregnancies complicated by TTTS who underwent FLPC in a single university‐affiliated tertiary medical‐center. Outcomes were compared between patients who received...

article

Epithelial IGF1R is dispensable for IGF2 mediated enhanced intestinal adaptation in retinoblastoma-deficient mice

Raphael C. Sun, Pamela M. Choi, Jose L. Diaz-Miron, Joshua Sommovilla, more

Journal of Pediatric Surgery > 2017 > 52 > 6 > 1026-1030

Previously, we demonstrated enhanced adaptation after small bowel resection (SBR) in intestinal-specific retinoblastoma (Rb)-deficient mice along with elevated levels of insulin-like growth factor 2 (IGF2) expression within the villi. The purpose of this study was to verify that the insulin-like growth factor 1 receptor (IGF1R) plays a role in this phenomenon.Inducible and intestinal specific Rb and...

article

Intestinal Epithelial-Specific mTORC1 Activation Enhances Intestinal Adaptation After Small Bowel Resection

Lauren Barron, Raphael C. Sun, Bola Aladegbami, Christopher R. Erwin, more

Cellular and Molecular Gastroenterology and Hepatology > 2017 > 3 > 2 > 231-244

Intestinal adaptation is a compensatory response to the massive loss of small intestine after surgical resection. We investigated the role of intestinal epithelial cell–specific mammalian target of rapamycin complex 1 (i-mTORC1) in intestinal adaptation after massive small bowel resection (SBR).We performed 50% proximal SBR on mice to study adaptation. To manipulate i-mTORC1 activity, Villin-Cre^ER...

article

Both epidermal growth factor and insulin-like growth factor receptors are dispensable for structural intestinal adaptation

Raphael C. Sun, Jose L. Diaz-Miron, Pamela M. Choi, Joshua Sommovilla, more

Journal of Pediatric Surgery > 2015 > 50 > 6 > 943-947

Purpose: Intestinal adaptation structurally represents increases in crypt depth and villus height in response to small bowel resection (SBR). Previously, we found that neither epidermal growth factor receptor (EGFR) nor insulin-like growth factor 1 receptor (IGF1R) function was individually required for normal adaptation. In this study, we sought to determine the effect of disrupting both EGFR and...

article

High-Protein Diet Improves Postoperative Weight Gain After Massive Small-Bowel Resection

Raphael C. Sun, Pamela M. Choi, Jose Diaz-Miron, Joshua Sommovilla, more

Journal of Gastrointestinal Surgery > 2015 > 19 > 3 > 451-457

Introduction Short bowel syndrome (SBS) is a morbid clinical condition that results from massive small-bowel resection (SBR). After SBR, there is a dramatic weight loss in the acute postoperative period. Our aim was to determine the impact of a high-protein diet (HPD) on weight gain and body composition in mice after SBR. Methods C57BL/6 mice underwent 50 % proximal SBR. Postoperatively,...

article

The role of enteral fat as a modulator of body composition after small bowel resection

Pamela M. Choi, Raphael C. Sun, Joshua Sommovilla, Jose Diaz-Miron, more

Surgery > 2014 > 156 > 2 > 412-418

After massive small bowel resection (SBR), a postoperative diet high in fat is associated with enhanced villus growth. The purpose of this study was to further elucidate the quantity and composition of enteral fat in structural and metabolic changes after SBR.C57/Bl6 mice underwent a 50% proximal SBR. Mice were then randomized to receive a low-fat diet (12% kcal fat), medium-fat diet (44% kcal fat),...

article

Tu1820 High Protein Diet (HPD) Improves Post-Operative Weight Gain After Massive Small Bowel Resection

Raphael C. Sun, Pamela M. Choi, Jose Diaz-Miron, Josh Sommovilla, more

Gastroenterology > 2014 > 146 > 5 Supplement 1 > S-1096-S-1097

article

Mo1796 IGF-2 Is Necessary for Retinoblastoma-Mediated Enhanced Adaptation After Small Bowel Resection

Pamela M. Choi, Raphael C. Sun, Josh Sommovilla, Jose Diaz-Miron, more

Gastroenterology > 2014 > 146 > 5 Supplement 1 > S-1073

article

974 Small Bowel Resection Induces Long-Term Changes in the Enteric Microbiome of Mice

Josh Sommovilla, Yanjiao Zhou, Raphael C. Sun, Pamela M. Choi, more

Gastroenterology > 2014 > 146 > 5 Supplement 1 > S-1033

article

High-Fat Diet Enhances Villus Growth During the Adaptation Response to Massive Proximal Small Bowel Resection

Pamela M. Choi, Raphael C. Sun, Jun Guo, Christopher R. Erwin, more

Journal of Gastrointestinal Surgery > 2014 > 18 > 2 > 286-294

Previous studies have shown that high-fat diet (HFD) enhances adaptation if provided immediately following small bowel resection (SBR). The purpose of this study was to determine if HFD could further enhance villus growth after resection-induced adaptation had already taken place. C57/Bl6 mice underwent a 50 % proximal SBR or sham operation and were then provided a standard rodent liquid diet (LD)...

article

IGF-2 Is Necessary for Retinoblastoma-Mediated Enhanced Adaptation after Small-Bowel Resection

Pamela M. Choi, Raphael C. Sun, Josh Sommovilla, Jose Diaz-Miron, more

Journal of Gastrointestinal Surgery > 2014 > 18 > 11 > 1887-1893

Previously, we have demonstrated that genetically disrupting retinoblastoma protein (Rb) expression in enterocytes results in taller villi, mimicking resection-induced adaption responses. Rb deficiency also results in elevated insulin-like growth factor-2 (IGF-2) expression in villus enterocytes. We propose that postoperative disruption of Rb results in enhanced adaptation which is driven by IGF-2...

article

A Comprehensive Assessment of Transfusion in Elective Pancreatectomy: Risk Factors and Complications

Raphael C. Sun, Anna M. Button, Brian J. Smith, Richard F. Leblond, more

Journal of Gastrointestinal Surgery > 2013 > 17 > 4 > 627-635

Background Specific data are needed regarding the impact of transfusion on operative complications in pancreatectomy. The objectives of this study were to determine risk factors for transfusion and to evaluate the potential association between transfusion and operative complications in elective pancreatectomy procedures. Study Design We reviewed our institution’s pancreatectomy and ACS-NSQIP databases...

article

Endovascular Management of Ruptured/Leaking Descending Thoracic and Visceral Aortic Aneurysms Using Branch Snorkels Technique

Mel J. Sharafuddin, Raphael C. Sun, Adonis J. Lysandrou, Parth B. Amin, more

Journal of Vascular Surgery > 2012 > 56 > 4 > 1191

article

Mo1507 Risk Factors, Hospital, Cost, and Complications Associated With Transfusion in Elective Pancreatectomy

Raphael C. Sun, Anna M. Button, Brian J. Smith, Hisakazu Hoshi, more

Gastroenterology > 2012 > 142 > 5 Supplement 1 > S-1081

Filter options

Publication date

Last 3 years (2)

Close

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

From:

To:
Set your own date range

INFONA - science communication portal

Search results for: Raphael C. Sun

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options