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We herein report a case of early primary duodenal carcinoma arising from Brunner’s glands synchronously occurring with sigmoid colon carcinoma. A 65-year-old man with a 5-year history of diabetes mellitus and benign prostatic hypertrophy was admitted to our hospital to undergo a resection of sigmoid colon carcinoma in December 2000. Upper gastrointestinal endoscopy, which was performed as routine...