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. Objective: Glucosamine, a naturally occurring amino monosaccharide has been used to treat or prevent osteoarthritis in humans. In this study, we evaluated the effect of glucosamine on rat adjuvant arthritis, a model of rheumatoid arthritis. Materials and methods: Adjuvant arthritis was induced in male Wistar rats by injection of Freund’s complete adjuvant (FCA) into the right hind paw, and 300 mg/kg...
. Objective: To evaluate the anti-thrombotic action of glucosamine, a naturally occurring amino monosaccharide, platelets were stimulated with ADP in the presence of glucosamine, and its effects on platelet functions were examined. Materials and Methods: Human platelet-rich plasma was stimulated with 2.5 μM ADP in the presence of glucosamine (0.01 ~ 1 mM) or other aminosugars (N-acetyl-glucosamine,...
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